分子生物・病理学的研究
分子生物・病理学的研究・
がん戦略研究・
ナノ医科学
分子生物・病理学的研究
乳腺の病態を解明する基礎的研究。
1.Miyashita M, Amano G, Ishida T, Tamaki K, Uchimura F, Ono T, Yajima M, Kuriya Y, Ohuchi N. The Clinical Significance of Breast MRI in the Management of Ductal Carcinoma In Situ Diagnosed on Needle Biopsy. Jpn J Clin Oncol. 2013 Apr 16.
2.Suzuki A, Ishida T, Ohuchi N. [Current status and problems of breast cancer screening in Japan]. Nihon Rinsho. 2012 Sep;70 Suppl 7:780-4. Japanese.
3.Tada H, Ishida T, Suzuki A, Ohuchi N. [Elements of informed consent in patients with diagnosed breast cancer]. Nihon Rinsho. 2012 Sep;70 Suppl 7:747-50. Japanese.
4.Watanabe G, Ishida T, Ohuchi N. [Adjuvant endocrine therapy for postmenopausal women]. Nihon Rinsho. 2012 Sep;70 Suppl 7:636-40. Japanese.
5.Tamaki K, Tamaki N, Kamada Y, Uehara K, Ohuchi N, Miyashita M, Ishida T, Sasano H. Clinical significance following breast conservation therapy with or without irradiation in breast cancer patients. Jpn J Clin Oncol. 2013 Mar;43(3):251-7.
6.Tamaki K, Ishida T, Tamaki N, Kamada Y, Uehara K, Miyashita M, Amari M, Tadano-Sato A, Takahashi Y, Watanabe M, McNamara K, Ohuchi N, Sasano H. Analysis of clinically relevant values of Ki-67 labeling index in Japanese breast cancer patients. Breast Cancer. 2012 Jul 11.
7.Ebata A, Suzuki T, Takagi K, Miki Y, Onodera Y, Nakamura Y, Fujishima F, Ishida K, Watanabe M, Tamaki K, Ishida T, Ohuchi N, Sasano H. Oestrogen-induced genes in ductal carcinoma in situ: their comparison with invasive ductal carcinoma. Endocr Relat Cancer. 2012 Jul 18;19(4):485-96.
8.Tamaki K, Ishida T, Miyashita M, Amari M, Ohuchi N, Kamada Y, Uehara K, Tamaki N, Sasano H. Breast ultrasonographic and histopathological characteristics without any mammographic abnormalities. Jpn J Clin Oncol. 2012 Mar;42(3):168-74.
9.Tamaki K, Ishida T, Miyashita M, Amari M, Mori N, Ohuchi N, Tamaki N, Sasano H. Multidetector row helical computed tomography for invasive ductal carcinoma of the breast: correlation between radiological findings and the corresponding biological characteristics of patients. Cancer Sci. 2012 Jan;103(1):67-72.
10.Miyashita M, Ishida T, Ishida K, Tamaki K, Amari M, Watanabe M, Ohuchi N, Sasano H. Histopathological subclassification of triple negative breast cancer using prognostic scoring system: five variables as candidates. Virchows Arch. 2011 Jan;458(1):65-72.
11.Tamaki K, Ishida T, Miyashita M, Amari M, Ohuchi N, Tamaki N, Sasano H. Correlation between mammographic findings and corresponding histopathology: potential predictors for biological characteristics of breast diseases. Cancer Sci. 2011 Dec;102(12):2179-85.
12.Tamaki K, Sasano H, Maruo Y, Takahashi Y, Miyashita M, Moriya T, Sato Y, Hirakawa H, Tamaki N, Watanabe M, Ishida T, Ohuchi N. Vasohibin-1 as a potential predictor of aggressive behavior of ductal carcinoma in situ of the breast. Cancer Sci. 2010 Apr;101(4):1051-8.
13.Tamaki K, Sasano H, Ishida T, Miyashita M, Takeda M, Amari M, Tamaki N, Ohuchi N. Comparison of core needle biopsy (CNB) and surgical specimens for accurate preoperative evaluation of ER, PgR and HER2 status of breast cancer patients. Cancer Sci. 2010 Sep;101(9):2074-9.
14.Oka K, Suzuki T, Onodera Y, Miki Y, Takagi K, Nagasaki S, Akahira J, Ishida T, Watanabe M, Hirakawa H, Ohuchi N, Sasano H. Nudix-type motif 2 in human breast carcinoma: a potent prognostic factor associated with cell proliferation. Int J Cancer. 2011 Apr 15;128(8):1770-82.
15.Tamaki K, Sasano H, Ishida T, Ishida K, Miyashita M, Takeda M, Amari M, Harada-Shoji N, Kawai M, Hayase T, Tamaki N, Ohuchi N. The correlation between ultrasonographic findings and pathologic features in breast disorders. Jpn J Clin Oncol. 2010 Oct;40(10):905-12.
16.Fukamachi K, Ishida T, Usami S, Takeda M, Watanabe M, Sasano H, Ohuchi N. Total-circumference intraoperative frozen section analysis reduces margin-positive rate in breast-conservation surgery. Jpn J Clin Oncol. 2010 Jun;40(6):513-20.
17.Amari M, Ishida T, Takeda M, Ohuchi N. Capecitabine monotherapy is efficient and safe in all line settings in patients with metastatic and advanced breast cancer. Jpn J Clin Oncol. 2010 Mar;40(3):188-93.
18.Watanabe G, Kato S, Nakata H, Ishida T, Ohuchi N, Ishioka C. alphaB-crystallin: a novel p53-target gene required for p53-dependent apoptosis. Cancer Sci. 2009 Dec;100(12):2368-75.
19.Ishida T, Kiba T, Takeda M, Matsuyama K, Teramukai S, Ishiwata R, Masuda N, Takatsuka Y, Noguchi S, Ishioka C, Fukushima M, Ohuchi N. Phase II study of capecitabine and trastuzumab combination chemotherapy in patients with HER2 overexpressing metastatic breast cancers resistant to both anthracyclines and taxanes. Cancer Chemother Pharmacol. 2009 Jul;64(2):361-9.
20.Ishida T, Tamaki K, Ohuchi N. [The current state of chemotherapy for breast cancer--the divergence between its continuation or discontinuation in outpatient chemotherapy]. Gan To Kagaku Ryoho. 2008 Dec;35 Suppl 1:97-9. Japanese.
21.Tamaki K, Moriya T, Sato Y, Ishida T, Maruo Y, Yoshinaga K, Ohuchi N, Sasano H. Vasohibin-1 in human breast carcinoma: a potential negative feedback regulator of angiogenesis. Cancer Sci. 2009 Jan;100(1):88-94.
22.Harada-Shoji N, Yamada T, Ishida T, Amari M, Suzuki A, Moriya T, Ohuchi N. Usefulness of lesion image mapping with multidetector-row helical computed tomography using a dedicated skin marker in breast-conserving surgery. Eur Radiol. 2009 Apr;19(4):868-74.
23.Ishida T, Takeda M, Suzuki A, Amari M, Moriya T, Ohuchi N. Significance of irradiation in breast-conserving treatment: comparison of local recurrence rates in irradiated and nonirradiated groups. Int J Clin Oncol. 2008 Feb;13(1):12-7.
24.Ohuchi N. Current topics in breast cancer clinical research, 2007. Int J Clin Oncol. 2008 Feb;13(1):1-2.
25.Ito M, Moriya T, Ishida T, Usami S, Kasajima A, Sasano H, Ohuchi N. Significance of pathological evaluation for lymphatic vessel invasion in invasive breast cancer. Breast Cancer. 2007;14(4):381-7.
26.Usami S, Moriya T, Amari M, Suzuki A, Ishida T, Sasano H, Ohuchi N. Reliability of prognostic factors in breast carcinoma determined by core needle biopsy. Jpn J Clin Oncol. 2007 Apr;37(4):250-5.
27.Usami S, Moriya T, Kasajima A, Suzuki A, Ishida T, Sasano H, Ohuchi N. Pathological aspects of core needle biopsy for non-palpable breast lesions. Breast Cancer. 2005;12(4):272-8. Review.
28.Amano G, Yajima M, Moroboshi Y, Kuriya Y, Ohuchi N. MRI accurately depicts underlying DCIS in a patient with Paget's disease of the breast without palpable mass and mammography findings. Jpn J Clin Oncol. 2005 Mar;35(3):149-53.
29.Takeda M, Ishida T, Ohnuki K, Suzuki A, Kiyohara H, Moriya T, Ohuchi N. Breast conserving surgery with primary volume replacement using a lateral tissue flap. Breast Cancer. 2005;12(1):16-20.
30.Moriya T, Hirakawa H, Suzuki T, Sasano H, Ohuchi N. Ductal Carcinoma in situ and related lesions of the breast: recent advances in pathology practice. Breast Cancer. 2004;11(4):325-33. Review.
31.Takeda M, Ishida T, Ohnuki K, Suzuki A, Sakayori M, Ishioka C, Nomizu T, Noguchi S, Matsubara Y, Ohuchi N. Collaboration of breast cancer clinic and genetic counseling division for BRCA1 and BRCA2 mutation family in Japan. Breast Cancer. 2004;11(1):30-2.
32.Amari M, Moriya T, Ishida T, Harada Y, Ohnuki K, Takeda M, Sasano H, Horii A, Ohuchi N. Loss of heterozygosity analyses of asynchronous lesions of ductal carcinoma in situ and invasive ductal carcinoma of the human breast. Jpn J Clin Oncol. 2003 Nov;33(11):556-62.
33.Ishida T, Ohnuki K, Takeda M, Suzuki A, Ohuchi N. [Treatment strategy for liver metastasis from breast cancer]. Nihon Geka Gakkai Zasshi. 2003 Oct;104(10):707-10. Japanese.
34.Shiraishi K, Kato S, Han SY, Liu W, Otsuka K, Sakayori M, Ishida T, Takeda M, Kanamaru R, Ohuchi N, Ishioka C. Isolation of temperature-sensitive p53 mutations from a comprehensive missense mutation library. J Biol Chem. 2004 Jan 2;279(1):348-55.
35.Ishida T, Furuta A, Moriya T, Ohuchi N. Pathological assessment of intraductal spread of carcinoma in relation to surgical margin state in breast-conserving surgery. Jpn J Clin Oncol. 2003 Apr;33(4):161-6.
36.Yoshida R, Ohuchi N, Kimura N. Clinicopathological study of chromogranin A, B and BRCA1 expression in node-negative breast carcinoma. Oncol Rep. 2002 Nov-Dec;9(6):1363-7.
37.Kimura N, Yoshida R, Shiraishi S, Pilichowska M, Ohuchi N. Chromogranin A and chromogranin B in noninvasive and invasive breast carcinoma. Endocr Pathol. 2002 Summer;13(2):117-22.